INT320153

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, IL6R) extracellular region (IL6, IL6R) aging (IL6)
plasma membrane (IL6R) enzyme binding (IL6R)
IL6 (Homo sapiens)
IL6R (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 70 78.44 Quite High
anakinra 5 72.40 Quite High
Pain 1 71.16 Quite High
corticosteroid 8 45.16 Quite Low
antagonist 1 40.36 Quite Low
rheumatoid arthritis 15 33.84 Quite Low
methotrexate 6 18.96 Low Low
cINOD 2 16.88 Low Low
withdrawal 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Exanthema 2 87.84 High High
Fever 7 87.36 High High
Juvenile Chronic Polyarthritis 63 78.44 Quite High
Experimental Arthritis 1 37.28 Quite Low
Rheumatoid Arthritis 15 33.84 Quite Low
Disease 21 25.92 Quite Low
INFLAMMATION 3 16.32 Low Low
Arthritis 6 5.00 Very Low Very Low Very Low
Osteoporosis 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The blockade of the biological functions of IL-6 may theoretically be available through a blockade of the gp130 receptor by neutralizing IL-6 or by the prevention of the IL-6/IL-6R complex formation.
Negative_regulation (prevention) of IL-6 Binding (formation) of IL-6R
1) Confidence 0.02 Published 2010 Journal Core evidence Section Body Doc Link PMC2899792 Disease Relevance 0.37 Pain Relevance 0.24

General Comments

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