INT320267

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CCNA2, CDK1) cytoplasm (CCNA2, CDK1) mitosis (CCNA2, CDK1)
nucleus (CCNA2, CDK1) cell division (CCNA2, CDK1) mitochondrion (CDK1)
CCNA2 (Homo sapiens)
CDK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 83.84 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 13 99.56 Very High Very High Very High
Malignant Neoplastic Disease 1 98.84 Very High Very High Very High
INFLAMMATION 3 83.60 Quite High
Liver Cancer 1 68.76 Quite High
Cirrhosis 2 66.36 Quite High
Cleidocranial Dysplasia 1 58.28 Quite High
Hepatitis C Virus Infection 2 57.56 Quite High
Hepatitis 3 51.56 Quite High
Infection 2 49.84 Quite Low
Cancer 11 42.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCNA2 activates CDC2 or CDK2 kinases and regulates the cell cycle positively by promoting G1/S and G2/M transitions in both the G1 and G2 phases of the cell cycle [54], while EGR1 (early growth response gene 1) has suppresses transformation [55].
CCNA2 Positive_regulation (activates) of CDC2
1) Confidence 0.12 Published 2010 Journal PLoS Computational Biology Section Body Doc Link PMC2900289 Disease Relevance 1.08 Pain Relevance 0.08

General Comments

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