INT320331

Context Info Confidence 0.39 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.05 Pain Relevance 0.03

extracellular space (Ighg2b)

Anatomy Link Frequency poly 2 Ighg2b (Mus musculus)

Pain Link Frequency Relevance Heat imagery 2 50.96 agonist 20 5.00 cytokine 10 5.00 Inflammation 4 5.00 Buprenorphine 4 5.00 ketamine 2 5.00 Pain management 2 5.00 Pain 2 5.00

Disease Link Frequency Relevance Heat Immunization 58 51.36 Myelodysplastic Syndromes 2 14.40 Infection 8 5.00 Influenza Virus Infection 6 5.00 Viral Infection 6 5.00 Pain 4 5.00 Targeted Disruption 4 5.00 Vesicular Stomatitis 4 5.00 INFLAMMATION 4 5.00 Sprains And Strains 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

S1 shows dose response of poly(I:C) on the production of NP-specific IgG2c and lack of polyclonal IgG2c production.

Negative_regulation (lack) of Gene_expression (production) of IgG2c in poly

1) Confidence 0.39 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0 Pain Relevance 0.03

The NP-specific mAb S43-10 (Reth et al., 1978) was used as a positive control for a high-affinity NP-specific IgG2c antibody with an affinities of Kd = 2.4 × 10?

Negative_regulation (affinity) of Gene_expression (antibody) of IgG2c

2) Confidence 0.34 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.