INT320398

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Psmb10, Psmf1) peptidase activity (Psmb10) cell morphogenesis (Psmb10)
nucleus (Psmb10)
Anatomy Link Frequency
neuronal 1
Psmb10 (Rattus norvegicus)
Psmf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
potassium channel 1 17.68 Low Low
Glutamate receptor 8 5.00 Very Low Very Low Very Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 2 99.88 Very High Very High Very High
Dementia 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Intellectual Impairment 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Aids-related Complex 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Ataxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is also noteworthy that we could not detect by mass spectrometry parkin (an E3 mutated in autosomal-recessive juvenile Parkinsonism) and PI31 (which may function as an inhibitor of the 20S proteasome), which have been reported to interact with proteasomes in non-neuronal cells (McCutchen-Maloney et al., 2000; Sakata et al., 2003).
proteasome Binding (interact) of PI31 in neuronal associated with parkinson's disease
1) Confidence 0.00 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2901091 Disease Relevance 0.10 Pain Relevance 0

General Comments

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