INT320400

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Vcp, Khdrbs1) nucleus (Vcp, Khdrbs1) transport (Vcp)
endoplasmic reticulum (Vcp) protein complex (Vcp) cytosol (Vcp)
Anatomy Link Frequency
neuronal 1
Vcp (Rattus norvegicus)
Khdrbs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 8 22.20 Low Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 4 68.00 Quite High
Dementia 4 43.60 Quite Low
Disease 3 37.28 Quite Low
Parkinson's Disease 2 34.96 Quite Low
Frontotemporal Dementia 1 31.12 Quite Low
Intellectual Impairment 3 29.96 Quite Low
Targeted Disruption 1 19.16 Low Low
Angelman Syndrome 1 17.44 Low Low
Depression 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data show that p62 and the VCP ATPase complex, both of which bind ubiquitylated proteins and assist degradation (Dreveny et al., 2004; Seibenhener et al., 2004), are associated with neuronal proteasomes.
VCP ATPase Binding (complex) of p62 in neuronal
1) Confidence 0.01 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2901091 Disease Relevance 0.07 Pain Relevance 0

General Comments

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