INT320420

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.14
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Psmb10) cell morphogenesis (Psmb10) nucleus (Psmb10)
cytoplasm (Psmb10)
Anatomy Link Frequency
brain 1
Psmb10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 24 71.44 Quite High
agonist 3 69.92 Quite High
tetrodotoxin 15 57.12 Quite High
nMDA receptor 6 43.04 Quite Low
potassium channel 3 28.56 Quite Low
depression 6 5.00 Very Low Very Low Very Low
Action potential 6 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 6 81.44 Quite High
Aids-related Complex 3 55.12 Quite High
Dementia 12 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Intellectual Impairment 9 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Aging 6 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Ataxia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This set differed from those in other tissues and we also found several proteins that associated only with either the cytosolic or the synaptic proteasome.
proteasome Binding (associated) of
1) Confidence 0.00 Published 2010 Journal Frontiers in Molecular Neuroscience Section Abstract Doc Link PMC2901091 Disease Relevance 0 Pain Relevance 0.07
The relatively low levels of VCP and one of its associated factors detected by mass spectrometry in purified 26S proteasomes are thus likely a result of VCP-proteasome interaction in brain, although we cannot formally rule out the potential interaction between VCP and the GST-UBL matrix.
proteasome Binding (interaction) of in brain
2) Confidence 0.00 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2901091 Disease Relevance 0.08 Pain Relevance 0
The degree of association between the E3s and the proteasome was determined by their co-sedimentation properties (at 100,000?
proteasome Binding (association) of
3) Confidence 0.00 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2901091 Disease Relevance 0.06 Pain Relevance 0.08

General Comments

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