INT320693

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.15
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C5, Il6) extracellular region (C5, Il6)
C5 (Rattus norvegicus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 100.00 Very High Very High Very High
cytokine 42 98.28 Very High Very High Very High
Inflammation 34 97.88 Very High Very High Very High
Inflammatory response 22 85.96 High High
cva 35 79.76 Quite High
vagus nerve 9 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 56 100.00 Very High Very High Very High
Systemic Inflammatory Response Syndrome 10 99.12 Very High Very High Very High
Multiple Organ Failure 8 92.76 High High
Sepsis 64 88.44 High High
Cv Unclassified Under Development 8 87.80 High High
Coagulation Disorder 2 84.16 Quite High
Pancreatitis 1 83.08 Quite High
Pneumonia 1 82.52 Quite High
Disease 1 81.48 Quite High
Hemorrhage 36 79.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to over production of TNF, IL-1, IL-2, IL-6, and IL-12, other inflammatory mediators such as C5a involve the complement cascade.
C5a Regulation (involve) of Gene_expression (production) of IL-6 associated with inflammatory mediators
1) Confidence 0.04 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2902015 Disease Relevance 2.15 Pain Relevance 0.34

General Comments

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