INT320699

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
plasma membrane (Ptger2) cell-cell signaling (IL2) signal transducer activity (Ptger2)
Anatomy Link Frequency
macrophages 3
immune system 2
natural killer cells 1
Ptger2 (Rattus norvegicus)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 89.04 High High
cINOD 126 73.04 Quite High
Inflammation 2 50.00 Quite Low
aspirin 36 33.52 Quite Low
alcohol 16 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Squamous Cell Neoplasms 4 79.04 Quite High
Head & Neck Cancer 12 77.56 Quite High
Recurrence 2 72.96 Quite High
Cancer 38 72.52 Quite High
Malignant Neoplastic Disease 4 59.08 Quite High
Metastasis 2 52.32 Quite High
Skin Cancer 6 50.00 Quite Low
INFLAMMATION 6 50.00 Quite Low
Obesity 18 21.12 Low Low
Hyperplasia 2 7.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased production of PGE2 also suppresses the immune system of patients with HNSCC by suppressing lymphokine production, T- and B-lymphocyte proliferation, and the cytotoxicity of natural killer cells and macrophages [33].
Gene_expression (production) of PGE2 in immune system Negative_regulation (suppressing) of Gene_expression (production) of lymphokine in macrophages
1) Confidence 0.00 Published 2010 Journal International Journal of Otolaryngology Section Body Doc Link PMC2902018 Disease Relevance 0.55 Pain Relevance 0.18
Increased production of PGE2 also suppresses the immune system of patients with HNSCC by suppressing lymphokine production, T- and B-lymphocyte proliferation, and the cytotoxicity of natural killer cells and macrophages [33].
Gene_expression (production) of PGE2 in immune system Negative_regulation (suppressing) of in natural killer cells Gene_expression (production) of lymphokine in macrophages
2) Confidence 0.00 Published 2010 Journal International Journal of Otolaryngology Section Body Doc Link PMC2902018 Disease Relevance 0.55 Pain Relevance 0.18

General Comments

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