INT320713

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NRAS, AKT1) plasma membrane (NRAS, AKT1) cell differentiation (AKT1)
nucleoplasm (AKT1) transport (AKT1) small molecule metabolic process (AKT1)
NRAS (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 1 99.36 Very High Very High Very High
Apoptosis 4 99.04 Very High Very High Very High
Melanoma 91 70.48 Quite High
Skin Cancer 62 68.44 Quite High
Chromosome Aberrations 10 67.84 Quite High
Aneuploidy 2 63.92 Quite High
Cancer 56 58.80 Quite High
Isochromosomes 1 45.76 Quite Low
Monosomy 20 28.08 Quite Low
Metastasis 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, NRAS binds and activates lipid kinase phosphoinositide-3 kinase (PI3K), thereby activating the AKT-pathway and preventing apoptosis [85].
NRAS Positive_regulation (activating) of AKT associated with apoptosis
1) Confidence 0.37 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902045 Disease Relevance 0.84 Pain Relevance 0

General Comments

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