INT320720

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TBX3)
TBX3 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Melanoma 273 99.40 Very High Very High Very High
Cancer 168 98.80 Very High Very High Very High
Skin Cancer 186 98.00 Very High Very High Very High
Metastasis 90 93.48 High High
Chromosome Aberrations 30 90.48 High High
Monosomy 60 89.44 High High
Disease 12 70.72 Quite High
Congenital Anomalies 12 61.12 Quite High
Isochromosomes 3 49.68 Quite Low
Apoptosis 12 29.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
New insights in UM, however, came about by gene expression profiling of UMs which were shown to cluster naturally in two classes with different prognosis [52–54].
Gene_expression (expression) of UMs associated with melanoma
1) Confidence 0.29 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902045 Disease Relevance 1.63 Pain Relevance 0
Several groups have shown that approximately 46% of UMs carry mutations in the GNAQ gene [27, 81, 104] (Table 2) turning GNAQ into an oncogene.
Gene_expression (mutations) of UMs
2) Confidence 0.25 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902045 Disease Relevance 1.24 Pain Relevance 0
Mutations of BRAF were shown to be absent in UMs [95, 99].
Gene_expression (Mutations) of UMs
3) Confidence 0.25 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902045 Disease Relevance 0.66 Pain Relevance 0

General Comments

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