INT320732

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PIK3CD) signal transduction (PIK3CD) plasma membrane (PIK3CD)
PIK3CD (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 2 99.16 Very High Very High Very High
Apoptosis 17 97.88 Very High Very High Very High
Skin Cancer 124 68.24 Quite High
Melanoma 182 68.16 Quite High
Chromosome Aberrations 20 67.64 Quite High
Aneuploidy 4 63.72 Quite High
Cancer 112 58.60 Quite High
Isochromosomes 2 43.44 Quite Low
Monosomy 40 27.88 Quite Low
Metastasis 61 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, NRAS binds and activates lipid kinase phosphoinositide-3 kinase (PI3K), thereby activating the AKT-pathway and preventing apoptosis [85].
PI3K Binding (binds) of associated with apoptosis
1) Confidence 0.20 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902045 Disease Relevance 0.83 Pain Relevance 0
Additionally, NRAS binds and activates lipid kinase phosphoinositide-3 kinase (PI3K), thereby activating the AKT-pathway and preventing apoptosis [85].
lipid kinase phosphoinositide-3 kinase Binding (binds) of associated with apoptosis
2) Confidence 0.17 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902045 Disease Relevance 0.83 Pain Relevance 0
We therefore speculate that PDCD10-OSM and PDCD10-VEGFR2 interactions may be regulated by the availability of PtdIns(3,4,5)P3 generated by PI3K.
PI3K Binding (generated) of
3) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909203 Disease Relevance 0 Pain Relevance 0

General Comments

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