INT320742

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Dsg4) plasma membrane (Dsg4)
Anatomy Link Frequency
upper 1
Dsg4 (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 39 88.40 High High
Bullous Skin Disease 180 83.24 Quite High
Blister 108 82.24 Quite High
Monilethrix 3 77.44 Quite High
Disease 24 76.24 Quite High
Skin Diseases 3 70.72 Quite High
Acantholysis 6 51.28 Quite High
Streptococcus Infection 3 14.64 Low Low
Skin Infection 15 11.84 Low Low
Targeted Disruption 129 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dsg4 expression is restricted to the highly differentiated upper cell layers.
Gene_expression (expression) of Dsg4 in upper
1) Confidence 0.31 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.63 Pain Relevance 0
Conversely, Dsg1 and Dsg4 expression is driven by cell differentiation.
Gene_expression (expression) of Dsg4
2) Confidence 0.31 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.46 Pain Relevance 0
Unlike Dsg1 and Dsg3, whose expression is restricted to complex stratified epithelia, Dsg2 and Dsg4 are expressed in a wide range of other cell types.
Gene_expression (expressed) of Dsg4
3) Confidence 0.14 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.22 Pain Relevance 0

General Comments

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