INT320745

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.87
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Dsg1a) plasma membrane (Dsg1a)
Anatomy Link Frequency
epidermis 2
Dsg1a (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bullous Skin Disease 120 93.92 High High
Targeted Disruption 86 88.96 High High
Blister 72 78.96 Quite High
Hyperplasia 2 8.96 Low Low
Congenital Anomalies 2 5.16 Low Low
Adhesions 26 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
Skin Infection 10 5.00 Very Low Very Low Very Low
Acantholysis 4 5.00 Very Low Very Low Very Low
Streptococcus Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that coexpression of Dsg2 with Dsg1 in the superficial epidermis may protect from the loss of Dsg1 by ETA although we cannot rule out the possibility that ectopic expression of Dsg2 may also impair the ETA-digestion of Dsg1 molecules.
Negative_regulation (impair) of Gene_expression (expression) of Dsg1 in epidermis
1) Confidence 0.43 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 1.06 Pain Relevance 0
Next, we assessed the expression and localization of Dsg1 (?
Negative_regulation (assessed) of Gene_expression (expression) of Dsg1
2) Confidence 0.43 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.81 Pain Relevance 0

General Comments

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