INT320759

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Context Info
Confidence 0.70
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Dsg1a) plasma membrane (Dsg1a)
Anatomy Link Frequency
skin 1
Dsg1a (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 129 99.36 Very High Very High Very High
Blister 108 90.80 High High
Bullous Skin Disease 180 50.00 Quite Low
Adhesions 39 5.00 Very Low Very Low Very Low
Disease 24 5.00 Very Low Very Low Very Low
Skin Infection 15 5.00 Very Low Very Low Very Low
Acantholysis 6 5.00 Very Low Very Low Very Low
Hyperplasia 3 5.00 Very Low Very Low Very Low
Streptococcus Infection 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the latter scenario is unlikely, as ETA is enzymatically efficient, and we did not observe any significant increase in uncleaved Dsg1 in ETA-treated Tg mice (see below).
Positive_regulation (increase) of Dsg1 associated with targeted disruption
1) Confidence 0.70 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 1.01 Pain Relevance 0
Interestingly, we observed a slight increase in Dsg1 in the ETA treated Tg skin (Figure 2(d)).
Positive_regulation (increase) of Dsg1 in skin associated with targeted disruption
2) Confidence 0.47 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.58 Pain Relevance 0
This increase in Dsg1 was reflected in a more intense 113?
Positive_regulation (increase) of Dsg1
3) Confidence 0.47 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.57 Pain Relevance 0

General Comments

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