INT320765

Context Info Confidence 0.48 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.74 Pain Relevance 0.13

plasma membrane (Dsg2, Akt1) transport (Akt1) aging (Akt1) enzyme binding (Akt1) carbohydrate metabolic process (Akt1) cytoplasm (Akt1)

Dsg2 (Mus musculus) Akt1 (Mus musculus)

Pain Link Frequency Relevance Heat cINOD 1 87.68 corticosteroid 1 84.96 imagery 1 5.00

Disease Link Frequency Relevance Heat Blister 36 93.44 Bullous Skin Disease 60 91.04 INFLAMMATION 1 87.44 Disease 8 72.56 Adhesions 13 66.16 Targeted Disruption 43 50.52 Skin Infection 5 5.00 Acantholysis 2 5.00 Hyperplasia 1 5.00 Streptococcus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

As mentioned above, we recently demonstrated that Dsg2 activates multiple growth and survival pathways, including PI 3-kinase/AKT, MEKMAPK, STAT3, and NF-?

Dsg2 Positive_regulation (activates) of AKT

1) Confidence 0.48 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 0.74 Pain Relevance 0.13

General Comments

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