INT320769
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Intriguingly, PF Ig had a minor effect on Dsg1-? | |||||||||||||||
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Thus, our results demonstrate that, at the Western blot level, PF Ig depletes Dsg1 and that superficial expression of Dsg2 in Tg mice did not appear to modulate the level of Dsg1 in response to PF Ig. | |||||||||||||||
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Next, we wanted to evaluate whether or not superficial expression of Dsg2 had an effect on Dsg1 fate and localization in response to PF Ig. | |||||||||||||||
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To test the effects of PF Ig on epidermal Dsg1, skin biopsies were collected after PF Ig treatment, and the total cellular proteins were extracted in Laemmli buffer. | |||||||||||||||
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General Comments
This test has worked.