INT320788

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (VEGFA, Flt1, Kdr) plasma membrane (Flt1, Kdr) kinase activity (Flt1, Kdr)
cell differentiation (Flt1) endosome (Flt1) Golgi apparatus (Flt1)
VEGFA (Homo sapiens)
Flt1 (Mus musculus)
Kdr (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 80.16 Quite High
Kinase C 1 71.60 Quite High
imagery 24 5.00 Very Low Very Low Very Low
positron emission tomography 7 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 5 89.36 High High
Cancer 92 84.72 Quite High
Hypoxia 3 74.48 Quite High
Hematological Disease 2 65.88 Quite High
Targeted Disruption 1 63.16 Quite High
Hypertension 4 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 4 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Pancreatic Cancer 3 5.00 Very Low Very Low Very Low
Hemorrhage 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Nrps can also bind to certain heparin binding isofoms of VEGF (e.g., VEGF165) to enhance the binding of VEGF to VEGFR1, and VEGFR2 (Figure 1) [31, 32].
VEGF Positive_regulation (enhance) of VEGFR1 Binding (binding) of VEGFR2
1) Confidence 0.15 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2902148 Disease Relevance 0.68 Pain Relevance 0.08

General Comments

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