INT320810

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYP27A1) extracellular space (COL1A2) small molecule metabolic process (CYP27A1)
extracellular region (COL1A2) protein binding, bridging (COL1A2)
Anatomy Link Frequency
Cleavage 3
COL1A2 (Homo sapiens)
CYP27A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 3 79.20 Quite High
Osteoarthritis 45 76.16 Quite High
Inflammation 1 72.08 Quite High
Arthritis 1 71.04 Quite High
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 22 97.24 Very High Very High Very High
Disease 5 94.16 High High
Osteoarthritis 45 76.16 Quite High
Arthritis 1 72.08 Quite High
Obesity 24 68.64 Quite High
Injury 1 68.28 Quite High
Stress 1 41.84 Quite Low
Sclerosis 1 28.68 Quite Low
Endometriosis (extended) 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cleavage of type I collagen results in release of C-terminal telopeptide of collagen type I (CTX-I) [20,21], which has been used extensively as a surrogate measure of bone resorption for in vitro, preclinical and clinical studies [20,22].
Protein_catabolism (Cleavage) of type I collagen in Cleavage Positive_regulation (results) of Localization (release) of CTX-I in Cleavage associated with hypercalcemia
1) Confidence 0.04 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2902412 Disease Relevance 1.05 Pain Relevance 0.40

General Comments

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