INT320842

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Context Info
Confidence 0.76
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Npc2) enzyme binding (Npc2) lysosome (Npc2)
Anatomy Link Frequency
hematopoietic stem cell 1
Npc2 (Mus musculus)
Pain Link Frequency Relevance Heat
antiepileptic Drug 2 55.84 Quite High
imagery 6 5.00 Very Low Very Low Very Low
peripheral neuropathy 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 2 96.24 Very High Very High Very High
Neurological Disease 14 84.08 Quite High
Disease 218 78.72 Quite High
Infection 2 75.08 Quite High
Sleep Disorders 26 69.88 Quite High
Contracture 2 68.24 Quite High
Spasticity 8 66.84 Quite High
Tremor 6 63.88 Quite High
Dystonia 22 63.44 Quite High
Convulsion 16 53.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the contrary, because the NPC2 protein is soluble, secreted and recaptured, there is a rationale supporting early hematopoietic stem cell transplantation in NP-C2 patients [82].
Localization (secreted) of NPC2 in hematopoietic stem cell
1) Confidence 0.76 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2902432 Disease Relevance 1.01 Pain Relevance 0.03
Contrary to the NPC1 protein, the NPC2 protein is small (132 amino acids), soluble, secreted and recaptured.
Localization (secreted) of NPC2
2) Confidence 0.76 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2902432 Disease Relevance 0 Pain Relevance 0

General Comments

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