INT320872

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.86
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Pla2g2a) extracellular space (Pla2g2a) endoplasmic reticulum (Pla2g2a)
Pla2g2a (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 1 90.88 High High
Inflammation 18 37.44 Quite Low
agonist 16 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
bradykinin 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 10 82.88 Quite High
Cancer 240 68.08 Quite High
Apoptosis 84 56.72 Quite High
Disease Progression 5 54.16 Quite High
Albuminuria 10 50.00 Quite Low
INFLAMMATION 18 37.44 Quite Low
Colon Cancer 140 5.00 Very Low Very Low Very Low
Metastasis 52 5.00 Very Low Very Low Very Low
Body Weight 32 5.00 Very Low Very Low Very Low
Hypertension 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas the expression of Cyp2c40 and 2c38 was unaffected by 5/6-Nx, sPLA2-mRNA expression was increased, suggesting a possible enhanced supply of CYP450-enzymes with arachidonic acid (Fig. 6A).
Positive_regulation (increased) of Gene_expression (expression) of sPLA2-mRNA
1) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2915917 Disease Relevance 0.14 Pain Relevance 0.05
Cultured cells were grown on superfrost slides and stained for phospholypase A2 (PLA2; Abcam, ab58375) and inducible nitric oxide synthase (iNOS; Abcam, ab15323) after 24 hours of treatment with 0.1 ?
Positive_regulation (stained) of Gene_expression (nitric oxide synthase) of PLA2
2) Confidence 0.25 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2902462 Disease Relevance 0.18 Pain Relevance 0
Cultured cells were grown on superfrost slides and stained for phospholypase A2 (PLA2; Abcam, ab58375) and inducible nitric oxide synthase (iNOS; Abcam, ab15323) after 24 hours of treatment with 0.1 ?
Positive_regulation (after) of Gene_expression (nitric oxide synthase) of PLA2
3) Confidence 0.25 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2902462 Disease Relevance 0.18 Pain Relevance 0
Cultured cells were grown on superfrost slides and stained for phospholypase A2 (PLA2; Abcam, ab58375) and inducible nitric oxide synthase (iNOS; Abcam, ab15323) after 24 hours of treatment with 0.1 ?
Positive_regulation (for) of Gene_expression (nitric oxide synthase) of PLA2
4) Confidence 0.25 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2902462 Disease Relevance 0.18 Pain Relevance 0
Cultured cells were grown on superfrost slides and stained for phospholypase A2 (PLA2; Abcam, ab58375) and inducible nitric oxide synthase (iNOS; Abcam, ab15323) after 24 hours of treatment with 0.1 ?
Positive_regulation (inducible) of Gene_expression (nitric oxide synthase) of PLA2
5) Confidence 0.25 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2902462 Disease Relevance 0.18 Pain Relevance 0

General Comments

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