INT320884

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.81
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Agtrap) endoplasmic reticulum (Agtrap) cytoplasm (VEGFA)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
Anatomy Link Frequency
pituitary 4
Agtrap (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 2 83.76 Quite High
agonist 8 81.12 Quite High
palliative 2 57.64 Quite High
bradykinin 2 5.28 Low Low
Disease Link Frequency Relevance Heat
Pituitary Cancer 8 99.68 Very High Very High Very High
Cancer 120 97.20 Very High Very High Very High
Immunotherapy Of Cancer 2 93.08 High High
Apoptosis 42 89.36 High High
Cv Unclassified Under Development 2 83.76 Quite High
Pheochromocytoma 2 80.72 Quite High
Colon Cancer 70 75.68 Quite High
Metastasis 26 75.20 Quite High
Death 2 52.84 Quite High
Malignant Neoplastic Disease 2 43.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both the AT1R and AT2R stimulate VEGF secretion by rat pituitary tumour cells [13] and the AT2R is highly expressed in intratumoural blood vessels of human pituitary adenomas[12].
AT1R Positive_regulation (stimulate) of Localization (secretion) of VEGF in pituitary associated with pituitary cancer
1) Confidence 0.10 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2902462 Disease Relevance 1.37 Pain Relevance 0.07
AT2R expression has been documented in blood vessels of human pituitary adenomas[12] and both the AT1R and AT2R stimulate vascular endothelial growth factor (VEGF) secretion by rat pituitary tumour cells [13].
AT1R Positive_regulation (stimulate) of Localization (secretion) of VEGF in pituitary associated with pituitary cancer
2) Confidence 0.07 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2902462 Disease Relevance 1.44 Pain Relevance 0.10

General Comments

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