INT320988

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.52
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gc) transport (Gc) extracellular space (Gc)
extracellular region (Gc)
Anatomy Link Frequency
pigmentation 1
Gc (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 123 99.70 Very High Very High Very High
Pain 3 61.92 Quite High
fibrosis 3 19.16 Low Low
tolerance 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Demyelination 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 126 99.70 Very High Very High Very High
Sunburn 3 99.70 Very High Very High Very High
Osteoporotic Fractures 3 97.24 Very High Very High Very High
Hypercalcemia 18 94.60 High High
Rickets 24 89.52 High High
Disease 20 75.00 Quite High
Chronic Progressive Multiple Sclerosis 1 72.76 Quite High
Convulsion 3 70.08 Quite High
Tetany 3 69.60 Quite High
Mobility Limitation 3 65.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the comparison of PP MScl versus RR MScl we observed a number of differentially abundant proteins, such as protein jagged-1 and vitamin D-binding protein.
Regulation (number) of vitamin D-binding protein associated with multiple sclerosis
1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2929207 Disease Relevance 1.25 Pain Relevance 0.55
Bischoff et al. [15] performed a meta-analysis of several small clinical studies that evaluated the effect of vitamin D treatment compared with control groups on the risk of falling and found that vitamin D replacement favored a reduction in number of falls, with an overall OR of about 0.75.


Regulation (effect) of vitamin D
2) Confidence 0.05 Published 2010 Journal Curr Rheumatol Rep Section Body Doc Link PMC2902729 Disease Relevance 0 Pain Relevance 0
A randomized, double-blind trial in the United Kingdom examined the effect of oral vitamin D supplementation on the risk of fracture in 2686 men and women 65 to 85 years of age who were living in the community.
Spec (examined) Regulation (effect) of vitamin D
3) Confidence 0.05 Published 2010 Journal Curr Rheumatol Rep Section Body Doc Link PMC2902729 Disease Relevance 1.10 Pain Relevance 0.06
The major source of vitamin D is sun exposure; thus, active vitamin D in the body can be affected by the season and the duration of direct exposure to sunlight and can be inhibited by sunscreen use and increased skin pigmentation.
Regulation (affected) of vitamin D in pigmentation associated with sunburn
4) Confidence 0.03 Published 2010 Journal Curr Rheumatol Rep Section Body Doc Link PMC2902729 Disease Relevance 0.16 Pain Relevance 0

General Comments

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