INT320992

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 4.23
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pecam1) cell adhesion (Pecam1) plasma membrane (Pecam1)
Anatomy Link Frequency
plug 4
neutrophils 3
lymphocytes 1
Pecam1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 108 98.44 Very High Very High Very High
Inflammation 60 84.32 Quite High
antagonist 24 76.32 Quite High
Hippocampus 32 51.76 Quite High
Central nervous system 4 50.00 Quite Low
Pyramidal cell 8 35.20 Quite Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 84 98.44 Very High Very High Very High
Myocardial Infarction 140 97.68 Very High Very High Very High
Obesity 8 96.64 Very High Very High Very High
Stroke 10 91.24 High High
INFLAMMATION 58 84.32 Quite High
Disease 24 79.44 Quite High
Adhesions 10 78.40 Quite High
Stress 102 74.16 Quite High
Death 20 65.68 Quite High
Cv General 4 Under Development 4 62.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The elevation of PECAM-1 in vessels is known to increase the transmigration of lymphocytes and neutrophils (Dangerfield et al., 2002; Michiels et al., 1998).
Positive_regulation (increase) of Positive_regulation (elevation) of PECAM-1 in neutrophils
1) Confidence 0.50 Published 2010 Journal Anatomy & Cell Biology Section Body Doc Link PMC2998780 Disease Relevance 1.28 Pain Relevance 0.31
Flow cytometric analysis showing a significant increase of LacZ+ cells in both Sca-1+ (b) and CD31+ (d) cell populations, parallel with an increase in total Sca+ (a) and CD31+ (c) cell numbers.
Positive_regulation (increase) of Positive_regulation (increase) of CD31
2) Confidence 0.30 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC2916122 Disease Relevance 0.81 Pain Relevance 0
Flow cytometric analysis indeed displayed a significant increase of LacZ+ cells in both Sca-1+ and CD31+ cell populations, parallel with an increase in total Sca+ and CD31+ cell numbers (Fig. 5a–d).
Positive_regulation (increase) of Positive_regulation (increase) of CD31
3) Confidence 0.30 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC2916122 Disease Relevance 0.43 Pain Relevance 0
The elevation of PECAM-1 in vessels is known to increase the transmigration of lymphocytes and neutrophils (Dangerfield et al., 2002; Michiels et al., 1998).
Positive_regulation (increase) of in lymphocytes Positive_regulation (elevation) of PECAM-1 in neutrophils
4) Confidence 0.17 Published 2010 Journal Anatomy & Cell Biology Section Body Doc Link PMC2998780 Disease Relevance 1.28 Pain Relevance 0.31
However, the addition of FGF-2 or C5a induced accumulation of CD31+ endothelial cells in the plugs and subsequent formation of microvascular-like structure (Fig. 7e–h).
Positive_regulation (induced) of Positive_regulation (accumulation) of CD31 in plugs
5) Confidence 0.09 Published 2010 Journal Inflamm Res Section Body Doc Link PMC2902742 Disease Relevance 0.09 Pain Relevance 0
In our experiments, the Matrigel plug containing C5a or FGF-2 showed increased accumulation of CD31+ endothelial cells and microvascular-like structure formation with infiltration of adipocytes.
Positive_regulation (increased) of Positive_regulation (accumulation) of CD31 in plug associated with obesity
6) Confidence 0.09 Published 2010 Journal Inflamm Res Section Body Doc Link PMC2902742 Disease Relevance 0.35 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox