INT321009

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ptpn6) phosphatase activity (Ptpn6) cell proliferation (Ptpn6)
nucleus (Ptpn6) cytoplasm (Ptpn6)
Anatomy Link Frequency
brain 2
Ptpn6 (Mus musculus)
Pain Link Frequency Relevance Heat
midbrain 1 99.68 Very High Very High Very High
analgesia 20 77.24 Quite High
Hyperalgesia 2 75.56 Quite High
bradykinin 4 74.72 Quite High
Nucleus accumbens 2 63.76 Quite High
Analgesic 38 59.12 Quite High
narcan 21 55.28 Quite High
Opioid 24 43.88 Quite Low
Spinal cord 6 36.08 Quite Low
opioid receptor 38 29.80 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 84.36 Quite High
Hyperalgesia 2 75.56 Quite High
Pain 14 5.00 Very Low Very Low Very Low
Nociception 5 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was surprised to note that Bestatin, which controlled the ME level in the midbrain, had no effect on the concentration of this peptide in the striatum, nor on the LE concentration in both parts of the brain studied.
Regulation (controlled) of Gene_expression (level) of ME in brain associated with midbrain
1) Confidence 0.05 Published 2010 Journal Frontiers in Neuroscience Section Body Doc Link PMC2903224 Disease Relevance 0.30 Pain Relevance 0.43

General Comments

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