INT321047

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Anpep, Ptpn6) phosphatase activity (Ptpn6) cell proliferation (Ptpn6)
peptidase activity (Anpep) nucleus (Ptpn6) cytoplasm (Ptpn6)
Anatomy Link Frequency
brain 2
Anpep (Mus musculus)
Ptpn6 (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 2 89.84 High High
midbrain 1 89.40 High High
Analgesic 38 85.20 High High
narcan 21 81.36 Quite High
analgesia 20 65.08 Quite High
Hyperalgesia 2 63.40 Quite High
bradykinin 4 62.56 Quite High
Antinociceptive 21 44.00 Quite Low
Opioid 24 31.72 Quite Low
Spinal cord 6 23.92 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 72.20 Quite High
Hyperalgesia 2 63.40 Quite High
Pain 14 5.00 Very Low Very Low Very Low
Nociception 5 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The selective action of Bestatin might indicate the regional differences of ME catabolism in the brain and also differences in the contribution of APN to the inactivation of ME and LE.
APN Regulation (contribution) of Negative_regulation (inactivation) of ME in brain
1) Confidence 0.01 Published 2010 Journal Frontiers in Neuroscience Section Body Doc Link PMC2903224 Disease Relevance 0.25 Pain Relevance 0.43

General Comments

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