INT321126

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0

extracellular region (F5, Lyz2) extracellular space (F5) hydrolase activity, acting on glycosyl bonds (Lyz2) cell adhesion (F5) plasma membrane (F5) cytoplasm (Lyz2)

F5 (Homo sapiens) Lyz2 (Mus musculus)

Pain Link Frequency Relevance Heat headache 1 5.00

Disease Link Frequency Relevance Heat Togavirus Infection 123 89.28 Infection 5 88.88 Papillomavirus Infection 1 40.40 Flavivirus Infection 1 34.64 Rabies Virus Infection 1 32.16 Severe Acute Respiratory Syndrome 1 30.64 Coronavirus Infection 1 30.24 Hepatitis 1 28.80 Hepatitis A Virus Infection 2 27.28 Dengue 1 26.40

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

F5 nIgG neutralizing activity was somewhat more reduced with vF5-5 virus than with vF5-3, suggesting that the deletion of Lys is more disruptive for F5 binding than the Lys to Glu substitution coupled with the Val deletion found in the vF5-3 virus.

Negative_regulation (disruptive) of F5 Binding (binding) of Lys

1) Confidence 0.00 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2903468 Disease Relevance 0.32 Pain Relevance 0

General Comments

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