INT32117

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Context Info
Confidence 0.23
First Reported 1988
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 10
Disease Relevance 3.61
Pain Relevance 3.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 1
skull 1
pituitary 1
synaptic vesicle 1
stem 1
us (Mus musculus)
Pain Link Frequency Relevance Heat
Dismenorea 29 100.00 Very High Very High Very High
menstrual migraine 6 100.00 Very High Very High Very High
ketamine 3 99.40 Very High Very High Very High
anesthesia 3 99.04 Very High Very High Very High
nud 1 98.68 Very High Very High Very High
deep brain stimulation 20 94.92 High High
Migraine 2 89.88 High High
imagery 35 89.32 High High
Serotonin 1 88.88 High High
Pyramidal cell 30 80.28 Quite High
Disease Link Frequency Relevance Heat
Reprotox - General 1 29 100.00 Very High Very High Very High
Menstral Migraine 6 100.00 Very High Very High Very High
Pressure And Volume Under Development 1 99.02 Very High Very High Very High
Dyspepsia 1 98.68 Very High Very High Very High
Shock 17 97.76 Very High Very High Very High
Migraine Without Aura 2 89.88 High High
Natriuresis 2 84.24 Quite High
Disease 5 74.52 Quite High
Cognitive Disorder 2 71.84 Quite High
Pain 15 53.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Retention of CS-US association learned under ketamine anesthesia.
CS-US Binding (association) of associated with anesthesia and ketamine
1) Confidence 0.23 Published 1988 Journal Brain Res. Section Title Doc Link 3219555 Disease Relevance 0.18 Pain Relevance 0.38
Coupling its ability to interact with biological tissues [5] and its noninvasive transmission through skull bone and other biological tissues in a focused manner [6]–[8], US holds promise as a potentially powerful neurostimulation tool [9], [10], which may be capable of replacing currently invasive DBS strategies.
US Binding (interact) of in skull associated with deep brain stimulation
2) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568804 Disease Relevance 0.07 Pain Relevance 0.15
We postulate however the mechanical nature of US and its interactions with neuronal membranes leads to the opening of mechanically sensitive voltage-gated channels.
US Binding (interactions) of in neuronal
3) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568804 Disease Relevance 0 Pain Relevance 0.04
Acoustic cavitation can occur when the intensity of US is sufficient to induce the resonation, expansion, and collapse of gas bodies present in some biological tissue.
US Binding (intensity) of associated with shock
4) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568804 Disease Relevance 0.10 Pain Relevance 0.24
Many of the hazards associated with US stem from its ability to induce large thermal fluctuations and/or cavitational damage in soft tissues.
US Binding (associated) of in stem
5) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568804 Disease Relevance 0.05 Pain Relevance 0.10
While we have studied the actions of US on neuronal activity by monitoring ionic conductance and synaptic vesicle exocytosis, we recognize US may influence signaling molecules capable of influencing neuronal function.
US Binding (recognize) of in synaptic vesicle
6) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568804 Disease Relevance 0 Pain Relevance 0
BACKGROUND: Dysphoric premenstrual syndrome (PMS) has been associated with serotonergic dysregulation, and serotonergic medications have been reported to alleviate the symptoms of PMS.
premenstrual syndrome Binding (associated) of associated with dismenorea
7) Confidence 0.00 Published 1997 Journal J Clin Psychiatry Section Abstract Doc Link 9378691 Disease Relevance 0.37 Pain Relevance 0.50
To characterize the symptoms associated with premenstrual syndrome (PMS), the menstrual symptom calendars of 100 women diagnosed with PMS were factor-analyzed.
premenstrual syndrome Spec (analyzed) Binding (associated) of associated with dismenorea
8) Confidence 0.00 Published 1989 Journal Obstet Gynecol Section Abstract Doc Link 2927856 Disease Relevance 0.44 Pain Relevance 0.37
The association of menstrual migraine with the premenstrual syndrome.
premenstrual syndrome Binding (association) of associated with menstrual migraine and dismenorea
9) Confidence 0.00 Published 1993 Journal Cephalalgia Section Title Doc Link 8313458 Disease Relevance 1.44 Pain Relevance 1.51
Because of the unique combination of physical (e.g. bloating, water retention) and psychological (e.g. mood, memory) symptoms associated with premenstrual syndrome (PMS), various hypothalamic and pituitary hormones have been implicated in the pathophysiology of PMS.
premenstrual syndrome Binding (associated) of in pituitary associated with pressure and volume under development, dismenorea and nud
10) Confidence 0.00 Published 1996 Journal Psychoneuroendocrinology Section Abstract Doc Link 8817732 Disease Relevance 0.95 Pain Relevance 0.64

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