INT32118

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Context Info
Confidence 0.39
First Reported 1989
Last Reported 2010
Negated 2
Speculated 1
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 3.05
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mcf2l) intracellular (Mcf2l) cytoplasm (Mcf2l)
Anatomy Link Frequency
Vim 1
globus pallidus 1
brain 1
cortex 1
Mcf2l (Mus musculus)
Pain Link Frequency Relevance Heat
deep brain stimulation 95 100.00 Very High Very High Very High
anesthesia 4 92.16 High High
isoflurane 1 91.72 High High
Thalamus 4 85.60 High High
Hippocampus 1 83.84 Quite High
medulla 1 81.12 Quite High
Pain 6 79.92 Quite High
imagery 4 79.52 Quite High
Thalamotomy 1 77.92 Quite High
fibrosis 6 75.72 Quite High
Disease Link Frequency Relevance Heat
Dystonia 112 99.44 Very High Very High Very High
Epilepsy 8 95.80 Very High Very High Very High
Tremor 11 94.44 High High
Duodenal Ulcer 5 92.84 High High
Focal Dystonia 6 87.52 High High
Pain 6 79.92 Quite High
Cystic Fibrosis 6 75.72 Quite High
Injury 2 73.52 Quite High
Ulcers 1 72.24 Quite High
Movement Disorders 6 62.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The long-term results achieved by the two participating centers did not differ although they used different techniques for defining and locating the targets of electrode implantation (center A ventriculography and stereotactic CT, center B stereotactic CT an image fusion with contrast enhanced MPRAGE), suggesting that the technique of target localization has no significant effect on the results of DBS in our study population.
Neg (no) Regulation (effect) of DBS associated with deep brain stimulation
1) Confidence 0.39 Published 2007 Journal BMC Neurol Section Body Doc Link PMC1847528 Disease Relevance 0.06 Pain Relevance 0.21
OBJECTIVE: To examine the effects of bilateral AN DBS on motor cortex excitability in epilepsy and compare these to the known effects of AEDs.
Spec (examine) Regulation (effects) of DBS in cortex
2) Confidence 0.34 Published 2006 Journal Neurology Section Body Doc Link 16505313 Disease Relevance 0 Pain Relevance 0
Animal models have shown efficacy of DBS at several brain regions, although not all animal studies have shown efficacy.
Regulation (efficacy) of DBS in brain
3) Confidence 0.21 Published 2009 Journal Neurol Clin Section Abstract Doc Link 19853222 Disease Relevance 0.37 Pain Relevance 0.16
The authors compared the sensitivity of DBS and TOF in the detection of residual neuromuscular blockade during clinical anaesthesia.
Regulation (sensitivity) of DBS
4) Confidence 0.16 Published 1989 Journal Anesthesiology Section Abstract Doc Link 2929994 Disease Relevance 0 Pain Relevance 0
Superfusion of CFTR(inh)-172 (0.1-10 microM) over the duodenal mucosa had no effect on basal DBS but at 10 microM inhibited acid-induced DBS, suggesting that its effect was limited to CFTR activation.
Neg (no) Regulation (effect) of DBS
5) Confidence 0.09 Published 2005 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 15905414 Disease Relevance 0.94 Pain Relevance 0.35
We also review the literature concerning the efficacy of Vim DBS for addressing dystonia.
Regulation (efficacy) of DBS in Vim associated with deep brain stimulation and dystonia
6) Confidence 0.02 Published 2010 Journal Stereotact Funct Neurosurg Section Abstract Doc Link 20197711 Disease Relevance 0.94 Pain Relevance 0.35
The DBS target of choice in dystonia is presently the globus pallidus internus (GPi).
Regulation (target) of DBS in globus pallidus associated with deep brain stimulation and dystonia
7) Confidence 0.01 Published 2010 Journal Brain Section Body Doc Link PMC2842517 Disease Relevance 0.73 Pain Relevance 0.27

General Comments

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