INT321180

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk2, Ntrk1) plasma membrane (Ntrk2, Ntrk1) kinase activity (Ntrk2, Ntrk1)
cytosol (Ntrk2) cytoplasm (Ntrk1)
Anatomy Link Frequency
brain 1
Ntrk2 (Mus musculus)
Ntrk1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 18 5.00 Very Low Very Low Very Low
antidepressant 10 5.00 Very Low Very Low Very Low
Glutamate 6 5.00 Very Low Very Low Very Low
Eae 5 5.00 Very Low Very Low Very Low
Nerve growth factor 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
trk B 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 16 30.72 Quite Low
Anxiety Disorder 23 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Ganglion Cysts 8 5.00 Very Low Very Low Very Low
Shock 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Neurological Disease 4 5.00 Very Low Very Low Very Low
Stroke 4 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RT-PCR analysis revealed no change of TrkA or TrkB in mouse brain upon deoxygedunin treatment (Figure S2B), indicating that deoxygedunin stimulates TrkB activation independent of Trk receptor transcriptional alteration.
TrkB Neg (no) Regulation (change) of TrkA in brain
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2903477 Disease Relevance 0 Pain Relevance 0

General Comments

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