INT321259

Context Info Confidence 0.20 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 2 Disease Relevance 2.25 Pain Relevance 0.21

MPEG1 (Homo sapiens)

Pain Link Frequency Relevance Heat carpal tunnel syndrome 12 86.72 Pain 4 53.76 Inflammation 2 49.36

Disease Link Frequency Relevance Heat Mucopolysaccharidosis I 56 99.22 Disease Progression 6 99.22 Disease 38 98.36 Spinal Cord Diseases 4 88.00 Coronary Heart Disease 6 87.36 Carpal Tunnel Syndrome 12 86.72 Cognitive Disorder 6 84.88 Congenital Anomalies 16 84.00 Hernia 26 83.76 Contracture 28 82.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In summary, Scheie syndrome usually emerges during childhood, and recognition of attenuated MPS I requires awareness of the multisystemic disease manifestations and their diverse presentation.

MPS I Binding (recognition) of associated with mucopolysaccharidosis i and disease

1) Confidence 0.20 Published 2010 Journal J Inherit Metab Dis Section Abstract Doc Link PMC2903709 Disease Relevance 1.59 Pain Relevance 0.16

Strikingly, the pattern of disease progression indicates that most clinical features associated with MPS I first appeared before the age of 12 years in the majority of patients.

MPS I Spec (appeared) Binding (associated) of associated with disease progression

2) Confidence 0.19 Published 2010 Journal J Inherit Metab Dis Section Body Doc Link PMC2903709 Disease Relevance 0.66 Pain Relevance 0.05

General Comments

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