INT321556

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ctsb) mitochondrion (Ctsb) extracellular space (Ctsb)
extracellular region (Ctsb) lysosome (Ctsb) cytoplasm (Ctsb)
Ctsb (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 4 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
central nervous system 1 5.00 Very Low Very Low Very Low
Inward rectifier potassium channel 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 28 67.12 Quite High
Cancer 38 52.88 Quite High
Glioma 33 50.00 Quite Low
Glioblastoma 11 14.12 Low Low
Injury 8 5.00 Very Low Very Low Very Low
Wound Healing 6 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 5 5.00 Very Low Very Low Very Low
Metastasis 3 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 3 5.00 Very Low Very Low Very Low
Volume Depletion And Dehydration 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduction in the mRNA levels of MMP-9, uPAR and cathepsin B in M-sh, U-sh and C-sh transfected 4910 cells indicated a downregulation of MMP-9, uPAR and cathespin B target mRNAs, the mechanism by which shRNAs are proposed to work [24], [25].
Negative_regulation (Reduction) of Transcription (levels) of cathepsin B
1) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2904700 Disease Relevance 0.18 Pain Relevance 0

General Comments

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