INT321598

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (TNF) extracellular matrix organization (TNF) protein complex assembly (MLL)
DNA binding (MLL) signal transduction (TNF) extracellular space (TNF)
MLL (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Etanercept 50 99.84 Very High Very High Very High
Arthritis 38 99.06 Very High Very High Very High
methotrexate 3 51.88 Quite High
corticosteroid 2 51.32 Quite High
cINOD 3 50.64 Quite High
Inflammation 7 49.56 Quite Low
spinal inflammation 1 41.12 Quite Low
psoriasis 2 34.28 Quite Low
cytokine 1 10.68 Low Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 35 99.06 Very High Very High Very High
Lymphatic System Cancer 28 94.92 High High
Leukemia 17 93.84 High High
Malignant Neoplastic Disease 38 85.80 High High
Necrosis 3 56.00 Quite High
Cancer 13 55.64 Quite High
Disease 15 53.00 Quite High
INFLAMMATION 7 49.56 Quite Low
Arthritis 3 45.60 Quite Low
Low Back Pain 1 41.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of the most commonly used TNF inhibitors to treat JIA is etanercept, a fully human soluble receptor Fc fusion protein that binds specifically to TNF.
Fc fusion protein Binding (binds) of TNF associated with etanercept and arthritis
1) Confidence 0.05 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2904755 Disease Relevance 1.07 Pain Relevance 0.49

General Comments

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