INT32163

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Context Info
Confidence 0.46
First Reported 1983
Last Reported 1985
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) cell-cell signaling (POMC) cytoplasm (POMC)
extracellular space (POMC) generation of precursor metabolites and energy (POMC) signal transduction (POMC)
CALM1 (Homo sapiens)
POMC (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 4 99.32 Very High Very High Very High
Potency 3 91.28 High High
opiate 5 91.04 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
des-(1-13) human beta-endorphin interacts with calmodulin.
calmodulin Binding (interacts) of beta-endorphin
1) Confidence 0.46 Published 1983 Journal Peptides Section Title Doc Link 6312432 Disease Relevance 0 Pain Relevance 0.22
An amino terminal deletion peptide of human beta-endorphin (beta-endorphin 13-31), synthesized using solid phase methods, was shown to interact with calmodulin by cross-linking with bis(sulfosuccinimidyl)suberate and by a gel permeation chromatographic technique.
calmodulin Binding (interact) of beta-endorphin
2) Confidence 0.39 Published 1985 Journal Mol. Pharmacol. Section Abstract Doc Link 2934615 Disease Relevance 0 Pain Relevance 0.18
An amino terminal deletion peptide of human beta-endorphin (beta-endorphin 13-31), synthesized using solid phase methods, was shown to interact with calmodulin by cross-linking with bis(sulfosuccinimidyl)suberate and by a gel permeation chromatographic technique.
calmodulin Binding (interact) of beta-endorphin
3) Confidence 0.39 Published 1985 Journal Mol. Pharmacol. Section Abstract Doc Link 2934615 Disease Relevance 0 Pain Relevance 0.17
Binding of a synthetic beta-endorphin peptide to calmodulin.
calmodulin Binding (Binding) of beta-endorphin
4) Confidence 0.34 Published 1985 Journal Mol. Pharmacol. Section Title Doc Link 2934615 Disease Relevance 0 Pain Relevance 0.18

General Comments

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