INT321755

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.88
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gsn) extracellular space (Gsn) vesicle-mediated transport (Gsn)
extracellular region (Gsn) cytoskeleton (Gsn) protein complex (Gsn)
Anatomy Link Frequency
filaments 1
Gsn (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 92.76 High High
Mechanotransduction 2 80.08 Quite High
TRP channel 2 77.28 Quite High
medulla 4 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wound Healing 2 93.52 High High
INFLAMMATION 2 92.76 High High
Stress 4 91.04 High High
Targeted Disruption 14 87.16 High High
Hemorrhage 2 75.84 Quite High
Body Weight 4 5.00 Very Low Very Low Very Low
Deafness 4 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Control of actin polymerisation could be exerted through the regulation of gelsolin and its activities in capping and severing actin filaments.
Regulation (regulation) of gelsolin in filaments
1) Confidence 0.54 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2905391 Disease Relevance 0.22 Pain Relevance 0.11
PIP2 plays an important role in the regulation of gelsolin function by binding to gelsolin and inhibiting its interaction with actin.
Regulation (regulation) of gelsolin
2) Confidence 0.40 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2905391 Disease Relevance 0.66 Pain Relevance 0.12

General Comments

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