INT32183

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Context Info
Confidence 0.46
First Reported 1985
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Col2a1) extracellular region (Col2a1) cytoplasm (Col2a1)
Anatomy Link Frequency
articular cartilage 2
Col2a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Arthritis 11 100.00 Very High Very High Very High
cINOD 1 74.00 Quite High
rheumatoid arthritis 1 69.24 Quite High
Osteoarthritis 27 50.00 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Arthritis 4 100.00 Very High Very High Very High
Arthritis 7 98.76 Very High Very High Very High
Injury 1 86.48 High High
Body Weight 16 77.04 Quite High
Rheumatoid Arthritis 2 69.24 Quite High
Immunization 1 59.60 Quite High
Osteoarthritis 27 50.00 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Endometriosis (extended) 8 5.00 Very Low Very Low Very Low
Hypercalcemia 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Suppression of Type II collagen arthritis can be induced by the prior intravenous treatment of rats with either Type II collagen or its constituent peptide alpha 1, (II) CB10.
Positive_regulation (induced) of Negative_regulation (Suppression) of Type II collagen associated with experimental arthritis and arthritis
1) Confidence 0.46 Published 1985 Journal Int J Tissue React Section Abstract Doc Link 2935508 Disease Relevance 0.80 Pain Relevance 0.49
Our findings show that ovariectomy induces a significant increase in the breakdown of collagen type II and subsequent articular cartilage erosion.
Positive_regulation (increase) of Negative_regulation (breakdown) of collagen type II in articular cartilage
2) Confidence 0.17 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC400436 Disease Relevance 0.21 Pain Relevance 0

General Comments

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