INT321916

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (DAO, Dao) peroxisome (DAO, Dao) small molecule metabolic process (DAO)
cellular nitrogen compound metabolic process (DAO)
DAO (Homo sapiens)
Dao (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 18 98.84 Very High Very High Very High
nMDA receptor 32 92.48 High High
Pain 16 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Analgesic 6 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 6 5.00 Very Low Very Low Very Low
Substantia nigra 4 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 44 98.28 Very High Very High Very High
Cognitive Disorder 26 95.00 High High
Psychosis 6 86.96 High High
Disease 6 73.52 Quite High
Pain 14 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Nephrotoxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
D-serine, a D-amino acid that is regulated by DAAO, is a potent, endogenous co-agonist of the N-methyl-D-aspartic acid (NMDA) receptor.
DAAO Regulation (regulated) of D-amino acid associated with agonist
1) Confidence 0.36 Published 2010 Journal The Open Medicinal Chemistry Journal Section Abstract Doc Link PMC2905773 Disease Relevance 0.60 Pain Relevance 0.10
DAAO regulation of D-amino acid levels has been associated with several physiological processes ranging from hormone secretion to synaptic transmission and cognition.
DAAO Regulation (regulation) of D-amino acid associated with cognitive disorder
2) Confidence 0.16 Published 2010 Journal The Open Medicinal Chemistry Journal Section Abstract Doc Link PMC2905773 Disease Relevance 0.24 Pain Relevance 0.03

General Comments

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