INT321981

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dpp4, Glp1r) peptidase activity (Dpp4) extracellular region (Dpp4)
cell adhesion (Dpp4) Golgi apparatus (Dpp4) endoplasmic reticulum (Dpp4)
Dpp4 (Rattus norvegicus)
Glp1r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 25 50.00 Quite Low
Chronic pancreatitis 2 31.28 Quite Low
fibrosis 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 7 96.12 Very High Very High Very High
Diabetes Mellitus 83 95.28 Very High Very High Very High
Hyperlipidemia 10 92.84 High High
Body Weight 13 91.08 High High
Insulin Resistance 13 87.28 High High
Obesity 12 58.56 Quite High
Disease 6 53.12 Quite High
INFLAMMATION 29 50.00 Quite Low
Stress 6 50.00 Quite Low
Pancreatitis 3 45.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Future studies from us will estimate the effects of this DPP-IV inhibitor on the enzyme activity/expression, as well as on levels of GLP-1 and glucagon, in order to have a more detailed picture of how the incretins pathway is affected and its relative contribution for the effects of sitagliptin here reported.
DPP-IV Regulation (effects) of GLP-1
1) Confidence 0.07 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2905949 Disease Relevance 1.06 Pain Relevance 0

General Comments

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