INT322015

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) plasma membrane (P2RX7)
Anatomy Link Frequency
macrophages 1
IL1B (Homo sapiens)
P2RX7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 19 98.24 Very High Very High Very High
Arthritis 1 95.16 Very High Very High Very High
Pain 1 90.84 High High
antagonist 11 89.28 High High
agonist 22 28.64 Quite Low
addiction 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 98.24 Very High Very High Very High
Disease 7 95.60 Very High Very High Very High
Arthritis 1 95.16 Very High Very High Very High
Targeted Disruption 2 92.72 High High
Pain 1 90.84 High High
Neointima 1 90.32 High High
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These chronic inflammatory conditions are likely to involve tissue macrophages, which are absolutely dependent on P2X7 receptor activity for IL-1?
IL-1 Binding (activity) of P2X7 in macrophages associated with inflammation
1) Confidence 0.07 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 1.00 Pain Relevance 0.37

General Comments

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