INT322016

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL1B, TLR4) aging (IL1B) intracellular (TLR4)
cytoplasm (TLR4) cell-cell signaling (IL1B) cytosol (IL1B)
IL1B (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 22 100.00 Very High Very High Very High
addiction 5 100.00 Very High Very High Very High
Inflammation 19 88.80 High High
cytokine 3 63.68 Quite High
antagonist 11 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 88.80 High High
Disease 7 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neointima 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g/ml); TLR4 agonist dose is reported to recruit different signaling proteins (55), which may account for some discrepancy over the ATP dependence and time course of IL-1?
IL-1 Binding (account) of TLR4 associated with addiction and agonist
1) Confidence 0.05 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 0.18 Pain Relevance 0.32

General Comments

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