INT322026

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TLR7) signal transduction (TLR7) endoplasmic reticulum (TLR7)
plasma membrane (TLR7) intracellular (TLR7) lysosome (TLR7)
Anatomy Link Frequency
monocytes 2
TLR7 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 99.32 Very High Very High Very High
Inflammation 19 61.92 Quite High
antagonist 11 37.12 Quite Low
agonist 22 29.24 Quite Low
addiction 5 15.12 Low Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 61.92 Quite High
Disease 7 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neointima 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data are consistent with observations showing that TLR8 engagement is more effective than TLR7 activation in inducing proinflammatory cytokine production from human monocytes (37).
Positive_regulation (inducing) of Positive_regulation (activation) of TLR7 in monocytes associated with cytokine
1) Confidence 0.40 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 0.06 Pain Relevance 0.08

General Comments

This test has worked.

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