INT322068

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 3.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MYLK2) cytoplasm (MYLK2)
MYLK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 196 99.48 Very High Very High Very High
Cancer 148 99.06 Very High Very High Very High
Disease 32 5.00 Very Low Very Low Very Low
Metastasis 12 5.00 Very Low Very Low Very Low
Pancreatitis 12 5.00 Very Low Very Low Very Low
Stomach Cancer 12 5.00 Very Low Very Low Very Low
Lung Cancer 12 5.00 Very Low Very Low Very Low
Adenocarcinoma 8 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 8 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Up-regulation of mannose-binding lectin 2 and myosin light chain kinase 2, which have not previously been implicated in pancreatic cancer, were observed.
myosin light chain kinase 2 Binding (binding) of associated with pancreatic cancer
1) Confidence 0.06 Published 2010 Journal BMC Gastroenterol Section Abstract Doc Link PMC2906412 Disease Relevance 0.87 Pain Relevance 0
Proteomics analysis of serum protein profiling in pancreatic cancer patients by DIGE: up-regulation of mannose-binding lectin 2 and myosin light chain kinase 2

Background

myosin light chain kinase 2 Binding (binding) of associated with pancreatic cancer
2) Confidence 0.06 Published 2010 Journal BMC Gastroenterol Section Title Doc Link PMC2906412 Disease Relevance 0.80 Pain Relevance 0
These two proteins 'mannose-binding lectin 2 and myosin light chain kinase 2' might be potential biomarkers for the diagnosis of the pancreatic cancer.



myosin light chain kinase 2 Binding (binding) of associated with pancreatic cancer
3) Confidence 0.06 Published 2010 Journal BMC Gastroenterol Section Abstract Doc Link PMC2906412 Disease Relevance 0.76 Pain Relevance 0
In an independent series of serum samples from 16 patients with pancreatic cancer and 16 non-cancer-bearing controls, increased levels of mannose-binding lectin 2 and myosin light chain kinase 2 were confirmed by western blot.


myosin light chain kinase 2 Binding (binding) of associated with cancer and pancreatic cancer
4) Confidence 0.06 Published 2010 Journal BMC Gastroenterol Section Abstract Doc Link PMC2906412 Disease Relevance 0.85 Pain Relevance 0

General Comments

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