INT322086

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 2.68
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OPN1SW) plasma membrane (OPN1SW) signal transducer activity (OPN1SW)
Anatomy Link Frequency
urine 12
blood 4
OPN1SW (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 24 97.22 Very High Very High Very High
Pain 32 95.56 Very High Very High Very High
imagery 56 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 32 95.56 Very High Very High Very High
Sprains And Strains 16 94.32 High High
Fatigue 240 93.52 High High
Chronic Fatigue Syndrome 88 54.92 Quite High
Cognitive Disorder 72 50.00 Quite Low
Muscle Weakness 24 33.88 Quite Low
Muscle Disease 40 25.68 Quite Low
Neuropathy 16 24.48 Low Low
Cramps 16 22.96 Low Low
Disease 56 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (effects) of Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
1) Confidence 0.02 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.40 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (effects) of Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
2) Confidence 0.02 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.33 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (participation) of Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
3) Confidence 0.02 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.33 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (participation) of Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
4) Confidence 0.02 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.28 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (effects) of in blood Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
5) Confidence 0.01 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.40 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (effects) of in blood Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
6) Confidence 0.01 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.33 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (participation) of in blood Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
7) Confidence 0.01 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.33 Pain Relevance 0.14
Secondary objectives of the FACTS-2-FSHD trial are:

- to evaluate the effects of AET and CBT on bodily functions and structures as defined by the International Classification of Functioning, Disability and Health (ICF): lower extremity muscle strength, pain, psychological well being, cardiovascular risk factors, aerobic exercise tolerance, sleeping pattern, as well as biomarkers in blood and urine and structural and metabolic muscle tissue characteristics. - to evaluate the effects of AET and CBT on the ICF level of activities: physical activity in daily life, self perceived functional status, and fall incidence. - to evaluate the effects of AET and CBT on the ICF level of participation: limitations in participation and autonomy and quality of life. - to evaluate the effects of AET and CBT on environmental and personal factors as defined by the ICF: coping style, illness cognitions, concentration problems, motivation, caregiver strain, experienced fatigue of the caregiver, social support and coping of the caregiver.


Regulation (participation) of in blood Regulation (effects) of CBT in urine associated with pain, tolerance, fatigue and sprains and strains
8) Confidence 0.01 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906431 Disease Relevance 0.28 Pain Relevance 0.14

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