INT322131

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prkcg, Trpv4) intracellular (Prkcg) cilium (Trpv4)
transmembrane transport (Trpv4) response to stress (Prkcg) cytoplasm (Prkcg)
Prkcg (Rattus norvegicus)
Trpv4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 24 99.40 Very High Very High Very High
Hyperalgesia 8 95.12 Very High Very High Very High
agonist 12 93.44 High High
dorsal root ganglion 32 74.76 Quite High
IPN 2 64.64 Quite High
Taxol 60 41.44 Quite Low
Pain 26 5.00 Very Low Very Low Very Low
Neuropathic pain 8 5.00 Very Low Very Low Very Low
Mechanosensation 6 5.00 Very Low Very Low Very Low
Mechanotransduction 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 28 100.00 Very High Very High Very High
Hyperalgesia 8 95.12 Very High Very High Very High
Neuroblastoma 2 76.04 Quite High
Ganglion Cysts 32 74.76 Quite High
Inflammatory Pain 2 64.64 Quite High
Pain 24 5.00 Very Low Very Low Very Low
Neuropathic Pain 10 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We find that TRPV4 physically interacts with tubulin, actin and neurofilament proteins as well as the nociceptive molecules PKC?
PKC Binding (interacts) of TRPV4 associated with nociception
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2906515 Disease Relevance 0.18 Pain Relevance 0.13
TRPV4-Ct forms a Ca2+-sensitive supra-molecular signaling complex made of actin, tubulin as well as nociceptive signaling components PKC?
PKC Binding (complex) of TRPV4 associated with nociception
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2906515 Disease Relevance 0.57 Pain Relevance 0.33

General Comments

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