INT322245

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Myh7) nucleus (Myh7) cytoplasm (Myh7)
Hcm (Mus musculus)
Myh7 (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 32 50.00 Quite Low
antagonist 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
5HT 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophic Cardiomyopathy 84 100.00 Very High Very High Very High
Disease 12 83.04 Quite High
Myocardial Infarction 14 80.12 Quite High
Hypertension 14 77.76 Quite High
Coronary Heart Disease 28 67.32 Quite High
Left Ventricular Hypertrophy 38 53.32 Quite High
Hypertrophy 16 5.00 Very Low Very Low Very Low
Cardiovascular Disease 8 5.00 Very Low Very Low Very Low
Heart Disease 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A total of 40 of the 245 HCM-patients had a mutation in the MYH7, MYBPC3, TPM1, TNNI3, or TNNT2 genes (Additional table 2).
HCM Binding (mutation) of MYH7 associated with hypertrophic cardiomyopathy
1) Confidence 0.11 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 0.85 Pain Relevance 0
Because MYH7 mutations have been associated with more severe forms of HCM compared to MYBPC3, we also compared the effect of the AT1R SNP according to the mutated gene.
HCM Binding (associated) of MYH7 associated with hypertrophic cardiomyopathy
2) Confidence 0.11 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 0.43 Pain Relevance 0

General Comments

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