INT322264

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.68
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (MPZ, TLR4) signal transduction (TLR4) structural molecule activity (MPZ)
intracellular (TLR4) cytoplasm (TLR4)
MPZ (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 9 97.48 Very High Very High Very High
Inflammation 80 96.88 Very High Very High Very High
cINOD 1 84.08 Quite High
Inflammatory response 5 68.36 Quite High
Inflammatory mediators 4 13.64 Low Low
agonist 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dengue Hemorrhagic Fever 205 100.00 Very High Very High Very High
INFLAMMATION 90 96.88 Very High Very High Very High
Dengue 88 94.88 High High
Disease 39 94.60 High High
Chronic Disease 1 87.52 High High
Syndrome 16 86.20 High High
Infection 29 79.72 Quite High
Shock 18 53.76 Quite High
Asthma 1 15.68 Low Low
Sepsis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, association of allelic polymorphisms of TLR4 with DSS suggested by De Kruif and colleagues [46] suggests that differential signalling through TLRs may contribute to the severity of dengue disease, as suspected for other pathologies [133].
DSS Binding (association) of TLR4 associated with dengue, dengue hemorrhagic fever and disease
1) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2907396 Disease Relevance 1.68 Pain Relevance 0.47

General Comments

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