INT322280

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.94
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PCSK9) extracellular space (PCSK9) extracellular region (PCSK9)
lysosome (PCSK9)
Anatomy Link Frequency
liver 1
PCSK9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 80 88.88 High High
cytokine 9 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dengue Hemorrhagic Fever 205 100.00 Very High Very High Very High
Disease 39 99.60 Very High Very High Very High
INFLAMMATION 90 88.88 High High
Dengue 88 52.72 Quite High
Infection 29 5.00 Very Low Very Low Very Low
Shock 18 5.00 Very Low Very Low Very Low
Syndrome 16 5.00 Very Low Very Low Very Low
Sepsis 5 5.00 Very Low Very Low Very Low
Critical Illness 3 5.00 Very Low Very Low Very Low
Fever 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the PCSK9 transcript, which encodes a secreted protein that decreases the recycling of LDL to the liver by inducing the degradation of liver LDL receptors [74], is also over-expressed in the DSS signature and highly associated with the disease phenotype.
PCSK9 Binding (associated) of in liver associated with dengue hemorrhagic fever and disease
1) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2907396 Disease Relevance 0.94 Pain Relevance 0.12

General Comments

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