INT322288

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CASR) signal transducer activity (CASR)
Anatomy Link Frequency
parathyroid 2
CASR (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 16 75.80 Quite High
analgesia 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bone Cancer 2 95.76 Very High Very High Very High
Congenital Anomalies 2 94.56 High High
Renal Disease 3 90.96 High High
Chronic Renal Failure 3 83.44 Quite High
Hypercalcemia 6 81.52 Quite High
Hypocalcemia 2 78.64 Quite High
Pain 16 75.80 Quite High
Hypertension 2 19.04 Low Low
Focal Segmental Glomerulosclerosis 2 16.24 Low Low
Fistula 2 6.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cinacalcet (Sensipar®, Amgen, USA), a type II calcimimetic, allosterically increases the sensitivity of the calcium-sensing receptor, lowering the threshold for activation, and thereby decreasing secretion of parathyroid hormone (PTH) [1].
Positive_regulation (increases) of Regulation (sensitivity) of calcium-sensing receptor in parathyroid
1) Confidence 0.38 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2907400 Disease Relevance 0.95 Pain Relevance 0.14

General Comments

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