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Context Info
Confidence 0.25
First Reported 1980
Last Reported 1986
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (SHBG)
Anatomy Link Frequency
Sertoli cell 2
SHBG (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 99.98 Very High Very High Very High
opiate 5 99.90 Very High Very High Very High
antagonist 1 94.72 High High
narcan 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 1 95.24 Very High Very High Very High
Opiate Addiction 1 94.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Early clinical studies suggested that opiates may interfere with sex hormone secretion.
Spec (may) Negative_regulation (interfere) of Localization (secretion) of sex hormone associated with opiate
1) Confidence 0.25 Published 1980 Journal Am J Psychiatry Section Abstract Doc Link 6774622 Disease Relevance 0.19 Pain Relevance 0.33
For example, MSHs increased cAMP accumulation and aromatase activity in these cells, while opioids inhibited Sertoli cell proliferation and androgen binding protein (ABP) secretion.
Negative_regulation (inhibited) of Localization (secretion) of androgen binding protein in Sertoli cell associated with opioid
2) Confidence 0.03 Published 1986 Journal Med. Biol. Section Abstract Doc Link 2939305 Disease Relevance 0 Pain Relevance 0.24

General Comments

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