INT322321

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Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.07
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PGK1) small molecule metabolic process (PGK1) carbohydrate metabolic process (PGK1)
cytoplasm (PGK1)
PGK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
gABA 41 77.28 Quite High
Neurotransmitter 6 64.72 Quite High
Glutamate 7 63.36 Quite High
Spinal cord 16 46.64 Quite Low
monoamine 4 44.32 Quite Low
cva 2 32.40 Quite Low
GABAergic 14 30.24 Quite Low
palliative 1 9.72 Low Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 43 92.96 High High
Umbilical Hernia 24 84.84 Quite High
Cleft Palate 16 84.24 Quite High
Targeted Disruption 36 65.68 Quite High
Coronary Heart Disease 4 54.68 Quite High
Non-small-cell Lung Cancer 13 35.84 Quite Low
Death 9 34.00 Quite Low
Pulmonary Embolism 2 33.20 Quite Low
Cancer 10 25.04 Quite Low
Malignant Neoplastic Disease 3 5.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that a loxP sequence and an frt-flanked phosphoglycerate kinase promoter-driven neomycin-resistance gene (PGK-Neo) inserted into intron 1 and the 3'-flanking region of the VGAT gene, respectively, do not affect the expression level of VGAT protein.
Gene_expression (expression) of PGK
1) Confidence 0.65 Published 2010 Journal Mol Brain Section Body Doc Link PMC3023674 Disease Relevance 0.62 Pain Relevance 0.19
The candidate genes Arb, Rpl32, Rpl4, Tbp, Polr2a, Hprt1, Pgk1, Ppia for each species and 18S ribosomal RNA were quantified by RT-qPCR.
Gene_expression (quantified) of Pgk1
2) Confidence 0.44 Published 2010 Journal BMC Mol Biol Section Body Doc Link PMC2907514 Disease Relevance 0.44 Pain Relevance 0
2M), phosphoglycerate kinase 1 (PGK1), succinate dehydrogenase complex subunit A (SDHA), hypoxanthine-guanine phosphoribosyltransferase (HPRT), and ribosomal protein L13 (RPL13) genes, and expressed in terms of arbitrary units (a.u.).

2.5.

Gene_expression (expressed) of PGK1
3) Confidence 0.40 Published 2010 Journal Journal of Nucleic Acids Section Body Doc Link PMC2911612 Disease Relevance 0 Pain Relevance 0
The two reactions that regenerate ATP in glycolysis are the phosphoglycerate kinase and pyruvate kinase reactions, resulting in 4 ATP from phase 2.
Gene_expression (reactions) of phosphoglycerate kinase
4) Confidence 0.04 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3005844 Disease Relevance 0 Pain Relevance 0

General Comments

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