INT322397

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egfr, Adarb1) intracellular (Egfr, Adarb1) nucleoplasm (Adarb1)
RNA binding (Adarb1) plasma membrane (Egfr) translation (Egfr)
Egfr (Rattus norvegicus)
Adarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 131 100.00 Very High Very High Very High
Visceral pain 15 84.72 Quite High
analgesia 20 82.56 Quite High
Opioid 12 80.40 Quite High
antagonist 37 71.92 Quite High
Analgesic 16 67.76 Quite High
Enkephalin 6 49.76 Quite Low
agonist 11 34.16 Quite Low
Pain 14 5.00 Very Low Very Low Very Low
Antinociceptive 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

15 84.72 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

32 5.00 Very Low Very Low Very Low
Pain 11 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Colitis 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar transactivation of opioid receptors by epidermal growth factor receptor has been recently described [44], however this is the first evidence of transactivation of MOR by activation of KATP channels.


epidermal growth factor receptor Positive_regulation (transactivation) of receptors associated with opioid receptor
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2908066 Disease Relevance 0 Pain Relevance 0.80

General Comments

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